Perricone Neuropeptide Deep Wrinkle Serum and Eye Therapy Duo

Perricone Neuropeptide Deep Wrinkle Serum and Eye Therapy Duo
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or 6 Easy Pays of $39.17

+ S&H and tax Good until November 17, 2018 2:59 a.m. ET

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What is it: Dr. Perricone's one-two punch for addressing the appearance of the signs of aging on the face and eye areas.

Who is it for: Anyone who is concerned about or who has the signs of aging on their face and eye areas.

Why is it different: Neuropeptide Deep Wrinkle Serum contains Dr. Perricone's "secret sauce" of ingredients that are specifically designed to address the appearance of the signs of aging around the face. Based on the results of an independent consumer use study, 77% of subjects reported an improvement in the appearance of lines and wrinkles five minutes after application. And after eight weeks of use, 90% reported that with continued use they continued to see improvement in the appearance of lines and wrinkles overall.

Neuropeptide Eye Cream contains a unique, neuro-oligopeptide complex that addresses the appearance of the most stubborn signs of aging in the eye area. In a consumer use study, after four weeks, 90% of users agreed they saw a reduction in the appearance of crow's-feet; 77% agreed they saw a reduction in the appearance of dark circles; 90% agreed they saw smoother, firmer, healthier-looking skin around their eyes; 82% agreed they saw a reduction in the appearance of crepiness around their eyes; and 80% agreed they saw a reduction in the appearance of rings under their eyes.

How do I use it: Apply Neuropeptide Deep Wrinkle Serum to targeted areas of the face where the signs of aging may appear, including the nasal labial folds, outer areas of the eye, upper areas of the lips, between the eyes, and on the forehead. Apply over other Perricone daily treatments both morning and evening.

Apply Neuropeptide Eye Therapy both morning and evening. Apply in a gentle patting motion around the eye.

From Perricone MD.


  • 1-fl oz Neuropeptide Deep Wrinkle Serum
  • 0.5-fl oz Neuropeptide Eye Therapy

Delivery Date Estimate

Reviews & Community QA

Perricone Neuropeptide Deep Wrinkle Serum and Eye Therapy Duo is rated 2.9 out of 5 by 10.
Rated 1 out of 5 by from Smelly The Nuro peptide cream smells so bad that I could not handle it. It smelled of rotten fish but worse. I don’t care how good it might make my skin look, I cannot bear to smell it again. It probably is the most disgusting smell I’ve ever experienced. It made me gag.
Date published: 2018-02-03
Rated 1 out of 5 by from Severe reaction to products When first put on severe burning sensation on face, then it goes downhill from there. Face got all red and inflamed. Actually bought 3 other products from this company and same thing happened and had to send them all back.
Date published: 2017-12-27
Rated 5 out of 5 by from At Last! I've used Dr Perricone products for years - when I could afford it - and before they ever came to QVC. Now with the Auto-Delivery here I can continuously use Perricone without having to change to another brand, and, best of all, it's so affordable! If you've ever read any of his books, you know Dr P's anti-aging scientific principles are right on the money. The other brands are copying him... I ordered the 3-pc Age-Defying Neuropeptide special with the Facial Conformer, Facial Cream and Acyl-Glutathione Eye Lid Serum in June (it's not available any longer), and am so happy with my results. Read Dr P's books and use the products FAITHFULLY!
Date published: 2017-09-15
Rated 1 out of 5 by from Don't waste your money You know you'd think I would have learned at almost 60 that all these skin care lines and all their claims are fine for TV but having tried so many of them including Dr. Perricone products I can honestly say that end result is a lot of money being spent with very little result. I think a good skin regime is a must but beware of expensive products and their on air results. What is aired is a VERY small segment of you and I hand selected of course! I have used a lot LESS expensive products and have achieved a good skin program with equal results spending far less then this line. I was hopeful when I purchased Dr. Perricone's products as I wanted to see some before and afters for myself. But I cancelled my auto delivery plan after a months use of his products, ( I've used various ones in the past too), and won't purchase anything else from him. Wished it would have delivered!! Also the neuropeptide facial cream smells so bad I have to hold my breath to apply it, YUCK!!
Date published: 2017-06-24
Rated 5 out of 5 by from Great Duo! This a great duo. The serum is amazing! I suggest you use it liberally, don't skimp. Within seconds of application, I can see my face unwrinkle, but only if I use a lot. The eye cream I use over the Acyl-glutathione serum, and at age 49, I have zero issues with my lids and under eye circles have diminished. I love Perricone products because they work and I never break out.
Date published: 2016-02-26
Rated 2 out of 5 by from Not what they say I have had a few orders of this....sometimes the wrinkle serum was great ...others it really sat on my skin and did nothing ...confusing at best. too much to not work all the time!!!
Date published: 2016-01-07
Rated 5 out of 5 by from FINALLY! 2 fantastic products together. YEAH! What a bargain. I was so glad to see these two products finally together. I religiously use three Perricone products. The Neuropeptide Facial cream (and now the night time), and neuropeptide Eye Therapy and the Neuropeptide Deep Wrinkle Serum. I've tried everything in this product line - because it works! And my conclusion (to what I can afford) is that I cannot do without these three products. This was the first line that showed me we CAN reverse time! I remember 2 to 3 weeks in....I had to do a double take back to my bathroom mirror - because I couldn't believe my face had changed - it was lifting up! Not only that....within another 2 weeks it improved even more. Then to convince myself I stopped using and within several weeks I saw my skin dropping. So I went right back. And I haven't stopped since. Please note, the eye cream took my eyes to the next level. I seriously do NOT have wrinkles around my eyes anymore....and I'm about to turn 56. It's our Secret!!!
Date published: 2015-08-28
Rated 5 out of 5 by from Really really works This eye product is expensive but it really works and tightens skin on lids of eye and skin under the eye I have many many eye products but this is the absolute best. I'm in auto delivery and would never want to be w/o...this product. The serum is easy to pat on and do not use too much. The product does it's job all day say 8am until bedtime leaving skin w/o wrinkles and a smooth texture and appearance.
Date published: 2015-05-15
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