Perricone MD Neuropeptide Facial Cream

2018 Customer Choice Beauty Award Nominee
Perricone MD Neuropeptide Facial Cream
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Now with an improved scent and texture, this Neuropeptide Facial Cream helps to address the appearance of skin texture, the loss of elasticity, and leaves skin looking youthful and glowing.

In a study when cutometer testing was used:

-91% showed improvement in skin elasticity immediately after use
-91% showed improvement in skin elasticity after four weeks
-94% showed improvement in skin firmness, tightness, and tone after four weeks

Based on a consumer survey after four weeks:

-94% of subjects were amazed by this product's multi-firming benefits
-91% agreed that Neuropeptide Facial Cream is the ultimate firming and tightening product

How do I use it: In the morning, apply the Neuropeptide Facial Cream onto targeted areas of a cleansed face, focusing on the contours of the cheeks, forehead and jawline. Follow with a Perricone MD moisturizer (not included).

Special tip: Massage it into the hairline, up behind the ears and behind the neck.

You may notice that the Neuropeptide Facial Cream has a very slight scent, but should dissipate after application.

From Perricone MD.


  • 2.5-fl oz Neuropeptide Facial Cream

Tune in to QVC for Perricone MD - Skin Care

Monday, October 1, 2018 from Midnight – 1 a.m., 3 – 4 a.m., 9 – 10 a.m., Noon – 1 p.m., 6 – 7 p.m. ET

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Reviews & Community QA

Perricone MD Neuropeptide Facial Cream is rated 2.4 out of 5 by 37.
Rated 1 out of 5 by from Odor?!? Perricon's Neuropeptide Facial Cream seems to work nicely but the nasty odor is very difficult to get beyond. I actually have to mask the odor with a different cream under my nose in order to use it. Fortunately, the neck cream from the same TSV doesn't have the same odor and I tend to use it all over instead of the cream in the tube. At that cost, it should NOT smell like this. I opened it too late to return it or it all would have gone back. It is EXTREMELY UNPLEASANT.
Date published: 2018-08-26
Rated 2 out of 5 by from Don't like fish smell of product This will be the last time I purchase Perricone Product due to the fish smell. I believe the last time i purchased the cream the hostess said the smell was improved. Ladies there are more products to spend our money on than the Perricone product line.
Date published: 2018-08-19
Rated 1 out of 5 by from New creamy formula not as good! Please, please bring back the thinner, slightly fishy smelling formula of "liquid gold" as a purchase choice (perhaps calling it "original formula). I don't know what was added to it to make it creamier and thicker with no odor but you RUINED the product. I had been using this for years with EXCELLENT results. It was like a face lift-in-a-bottle! I'm 68 and everyone guesses that I'm in my early 50's....all of my noticeable wrinkles are gone!! The "new formula" has zero firming benefits.
Date published: 2018-08-02
Rated 5 out of 5 by from Best Firming cream I've been using Perricone products for over 10 years. His products are the best. This firming cream make your skin so beautiful. I'm 70 and people can't believe are great my skin is. Get over smell it made with dame which make this a firming cream. Love love it and firming moisturizer. Use all his products.☺
Date published: 2018-06-25
Rated 2 out of 5 by from Unhappy with new thicker formulation I have used Perricone MD Neuropeptide Facial Cream for several years with great results. Yes it was a bit runny and did smell for a short time after application, however the results were amazing. The new formulation is thick and difficult for my skin to absorb. The worst part of the new formulation is that my skin has started to break out. I have not had that problem since I was a teenager. Please give us the option for the old "thinner" product which I loved and would never be without. I do not think I will be using the new formulation.
Date published: 2018-06-09
Rated 5 out of 5 by from Miracle line eraser!!!’ I have tried all of qvc and high end department store brands and this is the only thing that truly works!!!!!! It actually has made my forehead lines and the line between my eyes disappear!!! I have never seen a product that actually removes lines !! This is the one and only true miracle worker to remove lines from your face!!!!
Date published: 2018-05-28
Rated 5 out of 5 by from Fabulous Great my deep labial line are less and less what make me more confident I was really sad about that but is ok now thank you Dr Perricone and QVC
Date published: 2018-05-21
Rated 1 out of 5 by from New Formulation Now I need to find a new cream. The new formulation is not working for me. Disappointed!
Date published: 2018-05-19
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