Perricone MD Neuropeptide Deep Wrinkle Serum 1oz.

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What is it: A fast-acting serum that contains Dr. Perricone's advanced technology to help improve the appearance of deep lines and wrinkles while helping to improve skin texture.

Who is it for: Anyone who is concerned about or has advanced signs of aging, specifically deep wrinkles.

Why is it different: Deep Wrinkle Serum works by delivering immediate benefits to the appearance of skin by helping to smooth the look of lines and wrinkles.

How do I use it: Apply two to four drops on targeted areas of the face where deep wrinkles exist, including the nasal labial lines, outer areas of the eye, upper areas of the lips, between the eyes, and on the forehead.

For Perricone MD skin-care routine: Apply after toner and before any other treatments or moisturizers.

From Perricone MD.

  • Net weight 1 oz

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A87563 — Perricone MD Neuropeptide Deep Wrinkle Serum 1oz.

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Rated 3.2 out of 5 by 100 reviewers.
Rated 5 out of 5 by Amazing ! It really does work! Buy this I have been using Perricone Neuropeptide Facial cream for about 5 yeas and I am now 67 years old. It worked beautifully for a while but I was loosing the race against aging sagging wrinkled skin. So I decided to add a serious serum that was in the mid price range of his products. This did it !!! My nasal folds down to my chin shrunk ! Yes They just withdrew. The wrinkles above my lips also reduced to almost being gone. I returned all the others, Denese, Roth, Philosophy. and re-ordered an even more expensive serum . His latest. What ever you can afford do it! I needed to know that my investment would pay off and it did. I will order this one also to use with my other Perricone products. Quit looking everywhere else. It really is a miracle before your eyes. It took about 3 weeks to see a remarkable difference. 08-27-15
Rated 5 out of 5 by Best Wrinkle Product on Market I have tried most wrinkle products out there. I have always thought this brand's neuropeptide products work better than any others, but this product is unbelievable. I have really deep 11 lines between my eyes, and using this once a day for 4 to 5 days all but makes them disappear. Same for the upper lip lines. This is the one product that I make sure never to run out of and use no matter what other products I am using or trying out. Highly, highly recommend. 01-19-15
Rated 5 out of 5 by Great Spot Treatment This reminds me of a product by the Canadian lab that works like a topical botox effect serum to relax the skin where repetitive movement lines appear. I use a mere drop per application and apply to my '1', smile lines near my eyes, rows of diagonal lines (not nasal labial folds)between my nose and lips, and the corners of my mouth. The diagonal lines have been there since my mid twenties, and 25 yrs later the lines are no deeper than they were then.What it does is relax the skin to smooth the creases to lessen the impact of repetitive facial movements. I use it at night so my lines are relaxed while I sleep. I use it in the morning and when I go out to soften lines. About halfway through my first bottle I noticed that even the most noticeable lines were barely visible. Combined with Tatcha cleanser p, Perricone facial firming moisturizer and argan oil, my skin is silky and smooth. Recently added Nuface and now have a firmer foundation to my skin as well. 11-15-14
Rated 5 out of 5 by This Is Perricone Skin-care At Its Finest! Yep- can't get around the fact that it's very expensive, but used with his evening repair cream? Oh boy!! It does everything it says and more. The pronounced lines ( that only recently made their debut appearance) are visibly reduced, and is not irritating. Get it if you can swing it. QVC how about this with the Evening repair and a HYDRATING eye cream in a kit??? As a TSV? Dr. Perricone, sometimes I think your philosophy is better looking skin through dehydration.... 11-11-14
Rated 4 out of 5 by May Not Work For Everyone.. I received this in one of the very first kits I purchased from QVC, quite some time back. I use as spot treatment and it's amazing how long this little bottle lasts! I know at the time I was about 56 or 57 - I'm 59 now.This worked well for me. Let me explain, I wouldn't describe my wrinkles as deep. My soft 1 (not 11) line- the furrow between the brows softened dramatically. It didn't work quite as well for the lower part of my face.. those tiny very fine lines from mouth to chin, which I blame on losing my back molars and waiting on dental implants. You must have your teeth to support your face or it will sink in and/or start developing fine lines. I must make more of an effort on those areas, as I try so many other products and forget I have this little gem in a corner of a dark cool drawer.Not all products work for everyone, but it's SO worth the 30 day test. I didn't really stick with it so diligently, as I'm only on my second bottle... but wouldn't want to be without it.!! Seriously, if you don't try you'll never know. I happen to think it's the best product Perricone sells besides the night-time product with Retinol, which of course takes longer to see results. Good luck to those who give this a go! :) 06-22-14
Rated 5 out of 5 by PERRICONE'S BEST PRODUCT EVER IN MY OPINION I love this deep wrinkle serum...I can feel my skin tighten as soon as I put it on. If I look away and then look back at my skin after the serum dries, I see an immediate, youthful glow as well as a firmer look. As far as I am concerned, this is Dr. Perricone's best product. I think it is a sleeper because it is not always presented but I love it! I am now purchasing it for the 6th time. Thank you QVC for selling this product. I use some of Dr. Perricone's other products but his is by far, my favorite! 06-13-14
Rated 4 out of 5 by Super Product Bought this after it was featured in some magazines. I love this product! 08-15-13
Rated 1 out of 5 by DISAPPOINTING I couldn't wait to get this home and try it. The TV representation of it made it sound fabulous. I have now been using it for several weeks, and wanted to make sure I followed the instructions exactly so that I wouldn't be stuck with it if it didn't work. AND it didn't. I have to say it has an instant effect, but not long lasting. I thought the product was more of a build-up effect that would continue to "better" my fine and deep lines and wrinkles. After about an hour I look the same as before putting the product on. Sadly it is going back, but I want SOMETHING that will work so I'll keep watching and trying. 03-29-12
Rated 1 out of 5 by Disappointed user I was thrilled to learn about this product and was anxious to receive and try. Save your $$$ I am sorry to report it has had no effect on my wrinkles and to be perfectly honest my skin looks dull since using. I have applied serum as directed and there has been no visible difference. It is an expensive and costly product ....I do not recommend you spend for this. 01-05-12
Rated 2 out of 5 by No difference For 10 months I have been putting this serum on half my face, with the Neuropeptide Firming Moisturizer. The other half of my face I used just JM Argon Oil. THERE IS NO difference. Are they both working or are they both not working......hard to tell. I am sticking to the Argon Oil and will find another product to experiment with! 01-01-12
Rated 5 out of 5 by ARE YOUR CREVISSES LIKE CAVES? …Especially the one or two between the eyebrows? I have had the ONE since my teens, never thought much about it until I began Q’ing four years ago. Before QVC and after, over time I became aware of more facial products that provide assistance to the deep-wrinkle dilemma. My attention immediately went to the ‘deep-one’, and the ‘less-deep half’ between my brows, as the wrinkles on my forehead were/are under control, and never was a problem, even for my current seventy-year young skin. I progressed to inheriting the lines in the lip area, including the ‘marionette’ marks, and the whole ‘shebang’! The latter were pretty much under control with philosophy™ (good products). Then bang! They began developing more pronounced plus the addition of a few more. MY SUCCESS WITH PERRICONE’S Neuropeptide Deep Wrinkle Serum over four-weeks is as follows: My ‘half’ has decreased to 75% gone! And the deeper, longer ‘one’ has decreased by 40% gone! The lip and nasal labial lines have improved by 85%!!! Hooray! Very noticeable and I am significantly ecstatic over the results... What next? I will dutifully keep using the Deep Wrinkle Serum ‘ad infinitum ‘, concentrating dually on all areas. I declare Perricone’s deep wrinkle serum a success for me, results were faster than I expected, the investment is worth every dollar, and I must add that the overall texture of my skin (with a defined, stick-to-it-regimen) has improved 90%! That is the key…. Keep going forward with anything that works for you. Thanks to QVC for easy-pays and TSV’s. P.S. I have had success and have reported on other Perricone products so far, with more to come… in other words: TBC… To Be Continued With Adds To The Perricone Crop! The key is to ‘keep on truckin’, have fun, and enjoy the process of healthy skin care! :-) PERSEVERANCE -- “‘Tis a lesson you should heed:/Try, try, try again./If at first you don’t succeed,/Try, try, try again.” --W. E. Hickson, ‘Try and Try Again’ 11-03-11
Rated 4 out of 5 by It Works!!! I just started using this and although my wrinkles are still there, I can say I noticed immediate results on the texture and look of my skin, use this twice a day. A winner from Dr. P!!! His products have made a huge difference in my skin. 08-30-11
  • 2016-05-02 T07:00:30.778-05:00
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