Perricone MD Ultimate Firming 4-piece Collection

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What is it: An AM/PM system containing three of Dr. Perricone's unique technologies and three of his best-selling products to help address the appearance of the visible signs of aging for the face, eye, and neck areas. DMAE Firming Pads is the icing on the cake, delivering targeted benefits to the skin.

Who is it for: Anyone who wants to address the appearance of the visible signs of aging in their face, eye, or neck areas.

Why is it different: Neuropeptide Facial Cream's combination of ingredients and delivery system was specifically formulated. Acyl-Glutathione Eyelid Serum is like no other eye product out there. For the first time, Dr. Perricone has discovered a way to help address the aging eyelid area. This serum helps improve the appearance of eye creases and overall appearance of the eye area. Neuropeptide Necolletage represents Dr. Perricone's treatment for both the neck and the decollete area. The DMAE firming pad glides along your skin delivering benefits--taking the definition of a treatment pad to a whole new level by delivering a multitude of results.

How do I use it: Apply Neuropeptide Facial Cream in the morning, massaging it gently all over the face and bringing up to the hairline and behind the ears. Apply a small amount more on targeted areas of the face, focusing along the contours of cheeks and forehead.

Apply eyelid serum morning and night directly to the eyelid area working up to the brow bone in gentle patting motions. Apply along the lower contours of the eyes and all along under the eyes also in gently patting motions.

Use Neuropeptide Necolletage both morning and evening. Apply in circular motions along the chin, neck, back of the neck, and down the entire decollete area.

Smooth one saturated firming pad all over a cleansed face, bringing down to the neck area in the morning or evening. Press saturated pad into skin and hold for a few seconds to help target specific areas of concern.

From Perricone MD.


  • 1-fl oz Neuropeptide Facial Cream
  • 0.5-fl oz Acyl-Glutathione Eyelid Serum
  • 2-fl oz Neuropeptide Necolletage
  • 90-count DMAE Firming Pads

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Reviews & Community QA

Rated 2.6 out of 5 by 27 reviewers.
Rated 1 out of 5 by I wouldn't recommend to anybody I use only once smell of the product was awful so I threw in to the garbage. 07-12-16
Rated 1 out of 5 by Disappointed I ordered this after seeing the instant results on TV. Now, I realize immediate results will not happen to everyone. But I expected SOMETHING and got a whole lot of nothing. It's been at least three months and there has been no noticeable change using any of these products. Very disappointed. 05-06-16
Rated 2 out of 5 by Disappointed I purchased these products with an open mind, particularly after having waited over ten years to finally make the decision to invest in the Perricone product line. After having used these products for two months, I can honestly say that I am not impressed with the results at all. I am disappointed because I was so excited that QVC offered them and was faithful to use them daily. I am a 60 year old woman and saw no change at all. Maybe it was just the wrong selection. Thanks 02-28-16
Rated 1 out of 5 by Save Your Money! I cancelled auto-ship after 40 days & zero results. This may be Dr. Perricone's worst collection. The eye serum bottle never pumped correctly so I open the cap to apply it. The décolletage pump doesn't work either & the serum smells like mildew. The firming cream is in a jar, the smell is offensive. I'd tolerate all of the bad odors if the products really worked, but they do not. 02-21-16
Rated 1 out of 5 by Not Good for Neck and Eyes As a devotee to the cream, I decided to purchase this to try the eye and neck products. I have been using both diligently for the past 3 weeks and will be sending the kit back. The eye product really seems to make the under eye area worse - dry and crater-like. The delivery system also not effective. Pump works sporadically and have to work hard to get the product out. Then it spurts and you lose valuable product. The neck product is also disappointing. Again, neck area seems drier and more wrinkled (and overall...my neck was in pretty good shape). Again, pump is temperamental. I did not use the pads and was planning to use the neuropoeptide cream as travel option. The whole kit will go back. I would not recommend this kit. It is not efficacious as described. 02-13-16
Rated 1 out of 5 by Terrible product!!! I have used these products for over forty days hoping to see a change in firmness ANYWHERE on my face or neck. There have been no visible results and I am now beyond my return time. Way too overpriced to receive NO results!!!! I will never believe Dana and her hype of these products!!! 02-10-16
Rated 1 out of 5 by Big disappointment I purchased this product at the end of December. It is now the middle of February and I have seen absolutely no improvement in my skin, as promised. I stuck with the routine hoping to see some change, but, to no avail. I wasted a lot of money. 02-09-16
Rated 1 out of 5 by Smells Fishy Eye lid serum seems to work. As for the rest I can't get past the fishy smell or the fact that the dog goes nuts wanting to lick it off. 01-25-16
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