Perricone MD Power of Neuropeptides Face & Neck Duo

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If Sold Separately: $553.32

or 6 Easy Pays of $36.16

+ S&H and tax Good until April 27, 2018 2:59 a.m. ET

Delivery Options:
Known as "liquid gold," Perricone MD's best-selling Neuropeptide Facial Cream helps address the appearance of the visible signs of aging. A rich, velvety, fast-absorbing cream makes this the ultimate everyday luxury.

In a study, when cutometer testing was used:
  • 91% showed improvement in skin elasticity immediately after use
  • 91% showed improvement in skin elasticity after four weeks
  • 94% showed improvement in skin firmness, tightness, and tone after four weeks

Neuropeptide Restorative Neck & Chest Therapy is a lightweight cream with broad spectrum SPF 25. And with this special offer, you'll be getting it in a super size!

In a study, after eight weeks:
  • When image analysis was used, 74% saw improvement in the appearance of skin texture on the neck and decollete
  • When Chroma Meter testing was used, 93.5% saw a reduction in the appearance of redness on the decollete
  • When cutometer testing was used, 80.64% saw improvement in skin firmness, tightness, and tone on the neck under the chin
  • When expert grading was used, 77.8% saw improvement in the appearance of photo damage on the decollete

How do I use it: In the morning, apply the Neuropeptide Facial Cream onto areas of a cleansed face, focusing on the contours of the cheeks, forehead, and jawline. Then, apply the Neuropeptide Restorative Neck & Chest Therapy liberally to neck and chest. Begin by massaging along the entire upper chest area in gentle circular motions, moving up the front and back of the neck.

You may notice that the Neuropeptide Facial Cream has a very slight scent, but it should dissipate after application.

From Perricone MD.


  • 4-fl oz Neuropeptide Restorative Neck & Chest Therapy
  • 2.5-fl oz Neuropeptide Facial Cream

Delivery Date Estimate

Reviews & Community QA

Perricone MD Power of Neuropeptides Face & Neck Duo is rated 2.9 out of 5 by 58.
Rated 1 out of 5 by from smelly face cream I thought the face cream has been reformulated - its texture and smell (supposed to be no fragrance). The texture of both creams were great and my face did not get oily as the day went on and only a slight odor in the face cream. After using the face cream for a little over a week, I noticed the odor became stronger - the further I squeezed product from the tube. Frankly, it smells like the fish market - bad fishy smell... and I've been to plenty of wet markets - I'm Asian. I wish this purchase wasn't a set; I would've loved to keep the neck cream and will just order it separately when it becomes available by itself.
Date published: 2018-04-24
Rated 2 out of 5 by from Dead fish smell! I ordered this mainly for the chest cream. The verdict is still out, but I have to say the facial cream is horrible! I don't even know if the results will be good or not. Regardless I would never use or order the facial cream again due to the horrible dead fish smell! They said there was no smell to this. It was supposed to be new and improved. WRONG!!
Date published: 2018-04-23
Rated 5 out of 5 by from Really Love these Products I read in other reviews that the smell of the face cream is a little off putting; yes it is, at first, but I guess I have become used to it because it doesn't bother me now. I love both of these products. They glide on and absorb quickly and feel wonderful on my skin. My neck does feel more hydrated and it looks smoother. I'm happy with this purchase and I bet any one considering these products will be too. A little spendy but I feel the price is worth the benefits.
Date published: 2018-04-23
Rated 5 out of 5 by from LOVE DR Perricone !!! I became a Dr P user last June while purchasing a TSV. I immediately saw results and fell in love with my 3 piece set. I'm so glad that I got the new Face and Neck Duo...I missed my liquid gold ....Love this new set with the Neck and Chest Cream...it's silky smooth, doesn't smell. Awesome product
Date published: 2018-04-23
Rated 1 out of 5 by from Just not for me The face cream does have an awful smell but I can get past that because of the benefits to my skin. The Neck cream made me break out in tiny little pimply-like bumps after about 4 days so will be returning both.
Date published: 2018-04-23
Rated 3 out of 5 by from Last try with Perricone Really, new scent. This face cream does have a bad scent and left a watery and burning feel to my eyes. I will say I absolutely love the neck cream. Funny thing is, it appears all the Perricone TSVs have a really good product paired with a bad product. I have wasted so much money returning Perricone TSVs.
Date published: 2018-04-22
Rated 2 out of 5 by from Facial Cream Extremely Fishy Smelling Love neck cream but cannot tolerate fishy smell of face cream, as other reviewers have said. We were told over and over again on air smell was completely neutralized and gone in the facial cream, but it IS extremely fishy. It would seem QVC and Dr Perricone should make this right to its customers and send out the unscented version of facial cream as stated in presentation no charge so that we don’t have to return entire thing.
Date published: 2018-04-22
Rated 2 out of 5 by from Liked the neck cream I liked the consistency and absorbability of the neck cream. The face cream worked immediately on the area above my lip but the smell was too much for me. I had purchased the neuropeptide facial cream from QVC a few years ago and sent it back due to the smell. In the recent TV presentation for the TSV offer the Perricobe rep said the smell had been removed and there was no scent. She was very clear about that however this was not the case. The fish smell is still there and there is no arguing that. No matter how excited a manufacturer’s rep is about a product they should not embellish the truth to that extent. I had to send the whole thing back although I wish I could have kept the neck cream.
Date published: 2018-04-22
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