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Perricone MD Neuropeptide Night Cream 2.5 oz.
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Perricone MD Neuropeptide Night Cream 2.5 oz.

QVC Price: $240.00

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Shipping & Handling: $8.72

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The One You've Been Seeking

"Dr. Perricone has done it again! He's created a product, years in the making, that no other Perricone product has ever been able to do... Dr. Perricone is using six new neuropeptides he hasn't used in any other product. This is the answer you've been waiting for to address those wrinkles."

—Dana Bledsoe

Application Protocol

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What is it: Neuropeptide Night Cream helps address the appearance of wrinkles, helps hydrate skin, softens skin's texture, and helps reduce the look of dry lines.

Who is it for: Anyone looking to help address the appearance of dry lines and wrinkles and help hydrate skin.

Why is it different: Dr. Perricone wanted to create what he refers to as the "ultimate tool" for addressing the appearance of wrinkles. He formulated it by using Neuro Oligopeptide Complex, which is formulated with six different neuropeptides. He combined this with other keynote technologies, along with his unique delivery system.

After four weeks of use in a consumer study, 83% reported an improvement in the appearance of fine lines and 83% saw improvement in the appearance of overall lines and wrinkles.

How do I use it: Neuropeptide Night Cream should always be your last product before you apply a moisturizer. You only need a dime-sized amount, because it's heavily concentrated. Massage it into the skin to activate it. Apply it up under the chin and jawline. Continue to massage it up behind the ears and around the eye area.

From Perricone MD.


  • 2.5-fl oz Neuropeptide Night Cream

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A252416 — Perricone MD Neuropeptide Night Cream 2.5 oz.

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a252416_ingredients.html A252416 Neuropeptide Night Cream

Ingredients: Water/Aqua/Eau, Glycerin, Isononyl Isononanoate, Pentaerythrityl
Tetraethylhexanoate, Cetearyl Alcohol, Butyrospermum Parkii (Shea) Butter, C12-20
Acid PEG-8 Ester, Dimethyl Isosorbide, C10-18 Triglycerides, Isodecyl Salicylate,
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Butylene Glycol,
Squalane, C12-15 Alkyl Benzoate, Dimethicone, Polymethyl Methacrylate, Dimethyl
MEA, Citric Acid, Phenoxyethanol, Fragrance/Parfum, Caprylyl Glycol, Tribehenin,
Coco-Glucoside, Polysorbate 60, Tyrosine, Pentylene Glycol, Potassium Sorbate,
Tocopheryl Acetate, Dipotassium Glycyrrhizate, Hesperidin Methyl Chalcone, Hexylene
Glycol, Ceramide 2, Sodium Hydroxide, Urea, Fructose, PEG-10 Rapeseed Sterol,
Disodium EDTA, Steareth-20, Allantoin, Trehalose, Sodium Lactate, Sodium Chloride,
Sodium PCA, Maltose, Acetyl Hexapeptide-8, Pentapeptide-18, Tetrapeptide-21,
Glucose, Sodium Hyaluronate, Dipeptide-2, Palmitoyl Tetrapeptide-7, Palmitoyl

Information provided by Perricone MD

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Perricone MD Neuropeptide Night Cream 2.5 oz. 3.5 5 15 15
It works! I tried this when a number of the Dr's products were on easy pay. It works great! My skin is soft and the fine lines are gone. A bunch of my friends have started using Botox. I am leary of doing that! When my friends thought I had gotten Botox because my skin looked so much better, I knew I had a winner! Yes, it is expensive but I have over double the amount of money this was invested in products that I will never use because they don't work! I will pay for this because it does work!!! Love it!! 07-20-14
LOVE I have been using this product since it first came out. I ordered on auto-delivery, and placed another auto-delivery of the same thing! I'm in love with this cream. I look forward to washing my face at night so that I can use the cream. I love the's very calming. My skin seems thicker, and looking in the mirror first thing in the morning is easier on the eyes.:) I'm 63 and have been using Dr. Perricone products since he started on QVC. This one is by far my favorite. I would like to take a bath in it! 07-10-14
Did nothing I really wanted this to work especially for the price. I used this every night and I have not seen a difference. 07-03-14
waste of money I can not believe that I purchased such an expensive item. Since Lisa was saying how great it was I actually believed it worked the way they said. It is not worth the money and does not work any better than similar items at Wal-Mart. I have used it for over six weeks and see no difference. 06-28-14
Not as Advertised I used this product faithfully ..... I could not see any difference. I would not recommend this product to anyone. VERY PRICEY!!! 06-26-14
Sorry, not worth the money. First time ever I spent so much money on beauty product. It is too late to return but will definitely not order again. I have been using it for a while and see no results. 05-22-14
Excellent Product I have been looking for a true night cream for years. I saw results in 2 weeks. The first time I knew the product works when women commented on how beautiful my skin looked. I knew it had to be the night cream. I had a stubborn fine line on my right face on my cheek. I've been trying to diminish it for months. After using htis product, it is GONE!! Not only that but my entire face looks fresh when I wake up in the morning with or without enough sleep. I have never spent over $100 for any facial product. This product is worth the money and you DO NOT have to use a lot of it. I works!! 05-05-14
smells nice I've been using this every night for about three weeks, and I saw good results right away. My face looks so much younger in the mornings now, so I even use it during the day. 04-24-14
Its Like Discovering The Fountain Of Youth! I waited a month to write a revue so I can give you an honest opinion. Can I just say wow?! My skin is more youthful its glowing when I wake up in the morning, its more toned and fine lines have diminished. 5 stars all the way! 04-22-14
Hope Springs Eternal I really really wanted this to be the perfect night cream, unfortunately it separates and i do shake it first, but I don't think it is supposed to be runny. Maybe I got a bad batch, this also happened with the Neuropeptide day version, so much so that it all came running out of the tube like milk. 04-13-14
GOOD NIGHT CREAM I just recently received this but I have to say Iam liking the results I'm seeing which are a softening of the wrinkles and smoother appearance of my skin in the am, that to me is a good thing. 04-07-14
Great Product Even though I have been using the Neuropeptide Night Cream for a short time, I already love it!! I apply it after using Cold Plasma, and I have found my wrinkles do not appear as deep. The overall appearance of my face appears brighter and just in general looks a little younger. Also, there is no unpleasant fragrance. 04-06-14

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