Perricone MD Neuropeptide Facial Cream

Perricone MD Neuropeptide Facial Cream
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Now with an improved scent and texture, this Neuropeptide Facial Cream helps to address the appearance of skin texture, the loss of elasticity, and leaves skin looking youthful and glowing.

In a study when cutometer testing was used:

-91% showed improvement in skin elasticity immediately after use
-91% showed improvement in skin elasticity after four weeks
-94% showed improvement in skin firmness, tightness, and tone after four weeks

Based on a consumer survey after four weeks:

-94% of subjects were amazed by this product's multi-firming benefits
-91% agreed that Neuropeptide Facial Cream is the ultimate firming and tightening product

How do I use it: In the morning, apply the Neuropeptide Facial Cream onto targeted areas of a cleansed face, focusing on the contours of the cheeks, forehead and jawline. Follow with a Perricone MD moisturizer (not included).

Special tip: Massage it into the hairline, up behind the ears and behind the neck.

You may notice that the Neuropeptide Facial Cream has a very slight scent, but should dissipate after application.

From Perricone MD.


  • 2.5-fl oz Neuropeptide Facial Cream

Delivery Date Estimate

Reviews & Community QA

Perricone MD Neuropeptide Facial Cream is rated 2.2 out of 5 by 30.
Rated 1 out of 5 by from New Formulation Now I need to find a new cream. The new formulation is not working for me. Disappointed!
Date published: 2018-05-19
Rated 1 out of 5 by from New formulation is not as good I used this for years and loved it but the new Formulation is runny and doesn’t work good. Why change to inferior product?
Date published: 2018-04-05
Rated 1 out of 5 by from New Formulation A Big Disappointment Used the original formulation for years and loved it. A pea size truly was sufficient for my entire face and did wonders. The scent and consistency of the original did not bother me in the least and a tube actually lasted me a bit longer than the 6 months Dana promises if used as a pea size in the morning. Over the past month I opened my first tube of the new creamy formula and do not like it at all. The consistency does not work into the skin as well as the original and is no longer similar to a serum texture. Because of the formula change, I will be lucky if a tube will now last 4 months as opposed to 6 months - and I am still using just a pea size. I hope the formula was not changed in order to mask a change in the percentage of active ingredients that were in the original. Was a percentage of the active ingredients cut down and replaced with a filler that is now marketed as a "creamier" texture? This is the only reason I can think of for the formulation change. I would much rather have a price increase and keep the original formula - slight scent and all (which never affected me like some others). The original was "liquid gold" and worth it to me for the results. This new formula is, for me, "fool's gold". I hope they bring back the original as an option and that perhaps Dana will address whether the percentage of active ingredients remain the same between the original and "improved" formula.
Date published: 2018-03-26
Rated 2 out of 5 by from Meh... Will Not Buy Again Can't truly tell that this does anything and completely agree with other reviewer, it smells like dead fish. My product was not runny, but there is no way I'll buy it again sorry to say.
Date published: 2018-03-19
Rated 2 out of 5 by from Alwful This stuff is over rated!! Extremely runny, smells really bad, and well breaks me out. I purchased it with a special ‘one time’ value and I’m cancelling it the other creams are good. Sub-d and face moisturizer. Spend your shopping dollars On something else!
Date published: 2018-03-18
Rated 1 out of 5 by from Disappointed I am only sorry I didn't return this on time. I could stand the smell if it did what it was supposed to do. I haven't noticed any improvement and I've tried religiously and was very hopeful.
Date published: 2018-03-12
Rated 3 out of 5 by from Horrid Odor...why?? I have always taken good care of my skin, so maybe this is why I do not see a dramatic improvement...I am giving it more time. But, why, on Gods green earth, does it have to be so runny and stink so bad??? OMG.
Date published: 2018-03-12
Rated 1 out of 5 by from Waste of money I have been using this product for almost six months and have not noticed any improvement in either skin firmness or diminishing fine lines and wrinkles. The price is not inexpensive and I feel sorry that I wasted my money on this useless cream. The smell is nauseating, smells of rotten fish!
Date published: 2018-02-24
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