Perricone MD Neuropeptide Facial Cream Duo

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If Sold Separately: $480.00

or 6 Easy Pays of $21.50

+ S&H and tax

Known as "Liquid Gold" at QVC, the best-selling Perricone MD Neuropeptide Facial Cream helps to address the appearance of the signs of aging.

Based on the results of a consumer survey, after one use:

-74% of participants reported a slight to very noticeable change in the appearance of the texture and smoothness of their skin
-72% of participants reported a slight to noticeable change in the appearance of skin firmness
-70% reported a slight to extremely noticeable change in the radiance of their skin

How do I use it: In the morning, apply Neuropeptide Facial Cream onto targeted areas of a cleansed face, focusing on the contours of the cheeks, forehead, and jawline. Follow with a Perricone MD moisturizer (not included).

Special tip: Massage it into the hairline, up behind the ears and behind the neck.

You may notice that Neuropeptide Facial Cream has a very slight scent, but should dissipate after application.

From Perricone MD.


  • Two 2.5-fl oz Neuropeptide Facial Creams

Delivery Date Estimate

Reviews & Community QA

Perricone MD Neuropeptide Facial Cream Duo is rated 2.5 out of 5 by 122.
Rated 1 out of 5 by from Not the Product for my Skin This is the second time I've tried this product. Before and after use, about a year apart, I was using organic skin care line. This product made my skin very dry, even giving me a dry patch under both eyes where skin is so sensitive. Otherwise, I do not consider my skin to be sensitive. I wanted to try again because I thought it was me; now I know this just isn't the product line for me.
Date published: 2018-01-07
Rated 1 out of 5 by from Stinks This is NOT the same as a previous order I had from QVC of this same product. I just finished the tube of my previous order and reordered because I liked it. However my previous tube did not have this odor. This is also extremely runny and very strange. It is going back. I don't care what it does - I am not spreading this stinking stuff all over my face.
Date published: 2018-01-07
Rated 1 out of 5 by from Save your money This item smells terrible. They said that it had a slight odor but it is terrible. I see no results and will be returning this item very soon.
Date published: 2018-01-07
Rated 1 out of 5 by from Strong Odor! Beware! Yuck! The description says slight scent, but will dissipate. This is not a slight scent, it's a strong fishy odor, not what you want to smell in the morning when you're getting ready for work. It makes me self-conscious throughout the day because of the smell, I'm not sure if it's dissipating or I'm just getting used to it. I am going to try to use it for a couple of weeks and see if I can get over the strong odor, but it will probably go back. Very disappointed.
Date published: 2018-01-06
Rated 2 out of 5 by from not for me I returned this promptly; the scent alone was a turn off. Hey, why take a shower then spread stinky cream onto the skin? How can a nice fragrance (perfume) be "iTSELF" when this is competing? Sorry.
Date published: 2018-01-05
Rated 1 out of 5 by from Euuuuuuu That Smell – Can’t You Smell That Smell? Extremely disappointed in this product. I‘m not sure if this product did anything to improve the appearance of my face but I do know the smell of this cream is of rotting dead fish - disgusting! I read other reviews that complained of the dead fish smell and should have listened. I also read reviews of the smell dissipating within seconds/minutes – ha! I was tired of my using my expensive Chanel 5 to mask the order of the smell. The directions called to bring the cream up around the neck and behind the ear area. Mistake – Mistake! I smelled the dead fish all day. Finally, the consistency of the cream was runny not a thick cream. When I squeezed the tube way more would come out or ooze out of the tube. There is no way anyone can possibly use that much of this smelly cream on their face all day or all night long! RETURNED!
Date published: 2018-01-05
Rated 1 out of 5 by from You get what you pay for I used this product a few years ago and gave up. It was part of a kit and I was not following the whole regime. When I saw this special, I decided to give it a try again. There is no odor to the product which could be good news but I think it's because this is a watered down version of what I had before. The product is so thin that even after shaking the tube I think it should be applied with a dropper. It is almost like water. No way is this a year's worth of product. My worst buy from QVC.
Date published: 2018-01-05
Rated 1 out of 5 by from I tried, but just too smelly. I tried to use the product but I could not get over the fishy smell. It does dissipate after some time but the initial odor lingers for a while. Sending back. I figured there must be other creams at this price for me to use that do not smell so bad.
Date published: 2018-01-04
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