Rated 3.2 out of 5 by 102
Rated 2 out of 5 by abzgirl Costly
Tried this and compared it to my normal brand. Watched for a change for three weeks. It equally matched the results of my normal "Oil of Olay". Returned it. Just to pricey for me. My regular treatment cost far less.
Rated 5 out of 5 by Norahlovesbeautyproducts This serum works if you use a little each day
This serum works if you use a little each day.
I had "chicken skin" texture on my neck and this serum cleared that up in one month of using it for some wrinkles which also smoothed out significantly.
Rated 5 out of 5 by JudyBP Amazing ! It really does work! Buy this
I have been using Perricone Neuropeptide Facial cream for about 5 yeas and I am now 67 years old. It worked beautifully for a while but I was loosing the race against aging sagging wrinkled skin. So I decided to add a serious serum that was in the mid price range of his products. This did it !!! My nasal folds down to my chin shrunk ! Yes They just withdrew. The wrinkles above my lips also reduced to almost being gone. I returned all the others, Denese, Roth, Philosophy. and re-ordered an even more expensive serum . His latest. What ever you can afford do it! I needed to know that my investment would pay off and it did. I will order this one also to use with my other Perricone products. Quit looking everywhere else. It really is a miracle before your eyes. It took about 3 weeks to see a remarkable difference.
Rated 5 out of 5 by vegasbabe Best Wrinkle Product on Market
I have tried most wrinkle products out there. I have always thought this brand's neuropeptide products work better than any others, but this product is unbelievable. I have really deep 11 lines between my eyes, and using this once a day for 4 to 5 days all but makes them disappear. Same for the upper lip lines. This is the one product that I make sure never to run out of and use no matter what other products I am using or trying out. Highly, highly recommend.
Rated 5 out of 5 by Tresmoi Great Spot Treatment
This reminds me of a product by the Canadian lab that works like a topical botox effect serum to relax the skin where repetitive movement lines appear. I use a mere drop per application and apply to my '1', smile lines near my eyes, rows of diagonal lines (not nasal labial folds)between my nose and lips, and the corners of my mouth. The diagonal lines have been there since my mid twenties, and 25 yrs later the lines are no deeper than they were then.What it does is relax the skin to smooth the creases to lessen the impact of repetitive facial movements. I use it at night so my lines are relaxed while I sleep. I use it in the morning and when I go out to soften lines. About halfway through my first bottle I noticed that even the most noticeable lines were barely visible. Combined with Tatcha cleanser p, Perricone facial firming moisturizer and argan oil, my skin is silky and smooth. Recently added Nuface and now have a firmer foundation to my skin as well.
Rated 5 out of 5 by AVRNYC This Is Perricone Skin-care At Its Finest!
Yep- can't get around the fact that it's very expensive, but used with his evening repair cream? Oh boy!! It does everything it says and more. The pronounced lines ( that only recently made their debut appearance) are visibly reduced, and is not irritating. Get it if you can swing it. QVC how about this with the Evening repair and a HYDRATING eye cream in a kit??? As a TSV? Dr. Perricone, sometimes I think your philosophy is better looking skin through dehydration....
Rated 4 out of 5 by Funloving May Not Work For Everyone..
I received this in one of the very first kits I purchased from QVC, quite some time back. I use as spot treatment and it's amazing how long this little bottle lasts! I know at the time I was about 56 or 57 - I'm 59 now.This worked well for me. Let me explain, I wouldn't describe my wrinkles as deep. My soft 1 (not 11) line- the furrow between the brows softened dramatically. It didn't work quite as well for the lower part of my face.. those tiny very fine lines from mouth to chin, which I blame on losing my back molars and waiting on dental implants. You must have your teeth to support your face or it will sink in and/or start developing fine lines. I must make more of an effort on those areas, as I try so many other products and forget I have this little gem in a corner of a dark cool drawer.Not all products work for everyone, but it's SO worth the 30 day test. I didn't really stick with it so diligently, as I'm only on my second bottle... but wouldn't want to be without it.!! Seriously, if you don't try you'll never know. I happen to think it's the best product Perricone sells besides the night-time product with Retinol, which of course takes longer to see results. Good luck to those who give this a go! :)
Rated 5 out of 5 by Q-T PERRICONE'S BEST PRODUCT EVER IN MY OPINION
I love this deep wrinkle serum...I can feel my skin tighten as soon as I put it on. If I look away and then look back at my skin after the serum dries, I see an immediate, youthful glow as well as a firmer look. As far as I am concerned, this is Dr. Perricone's best product. I think it is a sleeper because it is not always presented but I love it! I am now purchasing it for the 6th time. Thank you QVC for selling this product. I use some of Dr. Perricone's other products but his is by far, my favorite!