Perricone MD Neuropeptide Deep Wrinkle Serum 1oz. Auto-Delivery

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What is it: A fast-acting serum that contains Dr. Perricone's advanced technology to help improve the appearance of deep lines and wrinkles while helping to improve skin texture. And thanks to this handy Auto-Delivery plan, you'll receive a new shipment approximately every 60 days for as long as you remain in the plan.

Who is it for: Anyone who is concerned about or has advanced signs of aging, specifically deep wrinkles.

Why is it different: Deep Wrinkle Serum works by delivering immediate benefits to the appearance of skin by helping to smooth the look of lines and wrinkles.

How do I use it: Apply two to four drops on targeted areas of the face where deep wrinkles exist, including the nasal labial lines, outer areas of the eye, upper areas of the lips, between the eyes, and on the forehead.

For Perricone MD skin-care routine: Apply after toner and before any other treatments or moisturizers.

From Perricone MD.

  • Each shipment includes 1-oz Neuropeptide Deep Wrinkle Serum; shipments arrive approximately every 60 days for as long as you remain in the program
  • Each shipment will be billed separately at the above price, plus shipping and handling and any applicable taxes, for as long as you remain in the plan; no obligation to continue the plan; cancel anytime

Important Details

If you take advantage of both Auto-Delivery and Easy Pay™, it is possible that more than one Easy Pay installment could be due in the same month. For example, if your Auto-Delivery plan ships every three months and you select 4 Easy Pay installments, you would pay the fourth installment of your first shipment in the same month you pay the first installment of your second shipment.

Delivery Date Estimate

Reviews & Community QA

Perricone MD Neuropeptide Deep Wrinkle Serum 1oz. Auto-Delivery is rated 3.2 out of 5 by 104.
Rated 1 out of 5 by from A lot of Hype! I have used several different Perricone products both from QVC and on line. They are far less effective than other less expensive products I have used. Perhaps they believe the high price will persuade women to think they are more effective but please don't be fooled. Even with continued use the results were hardly worth the price paid.
Date published: 2016-12-31
Rated 2 out of 5 by from Costly Tried this and compared it to my normal brand. Watched for a change for three weeks. It equally matched the results of my normal "Oil of Olay". Returned it. Just to pricey for me. My regular treatment cost far less.
Date published: 2016-12-27
Rated 5 out of 5 by from This serum works if you use a little each day This serum works if you use a little each day. I had "chicken skin" texture on my neck and this serum cleared that up in one month of using it for some wrinkles which also smoothed out significantly.
Date published: 2016-12-17
Rated 5 out of 5 by from Amazing ! It really does work! Buy this I have been using Perricone Neuropeptide Facial cream for about 5 yeas and I am now 67 years old. It worked beautifully for a while but I was loosing the race against aging sagging wrinkled skin. So I decided to add a serious serum that was in the mid price range of his products. This did it !!! My nasal folds down to my chin shrunk ! Yes They just withdrew. The wrinkles above my lips also reduced to almost being gone. I returned all the others, Denese, Roth, Philosophy. and re-ordered an even more expensive serum . His latest. What ever you can afford do it! I needed to know that my investment would pay off and it did. I will order this one also to use with my other Perricone products. Quit looking everywhere else. It really is a miracle before your eyes. It took about 3 weeks to see a remarkable difference.
Date published: 2015-08-27
Rated 5 out of 5 by from LOVE LOVE LOVE This is my favorite serum of all times. My skin is sensitive and this has always been gentle and effective for me. I've tried all of Dr. Perricone's serums (and most of the other brands as well) but to me this is by far the best for me. I can see a difference immediately and with use over time it gets better, and it is not harsh. Many of the other serums in other brands exfoliate and my skin becomes red. Not so with this serum. I'm so happy to see it once again offered on EZ pay on auto-delivery at QVC. My entire skincare regimen is Perricone because it works. It's expensive, yes, but it is worth every penny. Thanks to QVC for the EZ pay. Thanks to Dr. Nicholas Perricone for these phenomenal products.
Date published: 2015-05-16
Rated 5 out of 5 by from Best Wrinkle Product on Market I have tried most wrinkle products out there. I have always thought this brand's neuropeptide products work better than any others, but this product is unbelievable. I have really deep 11 lines between my eyes, and using this once a day for 4 to 5 days all but makes them disappear. Same for the upper lip lines. This is the one product that I make sure never to run out of and use no matter what other products I am using or trying out. Highly, highly recommend.
Date published: 2015-01-19
Rated 5 out of 5 by from Great Spot Treatment This reminds me of a product by the Canadian lab that works like a topical botox effect serum to relax the skin where repetitive movement lines appear. I use a mere drop per application and apply to my '1', smile lines near my eyes, rows of diagonal lines (not nasal labial folds)between my nose and lips, and the corners of my mouth. The diagonal lines have been there since my mid twenties, and 25 yrs later the lines are no deeper than they were then.What it does is relax the skin to smooth the creases to lessen the impact of repetitive facial movements. I use it at night so my lines are relaxed while I sleep. I use it in the morning and when I go out to soften lines. About halfway through my first bottle I noticed that even the most noticeable lines were barely visible. Combined with Tatcha cleanser p, Perricone facial firming moisturizer and argan oil, my skin is silky and smooth. Recently added Nuface and now have a firmer foundation to my skin as well.
Date published: 2014-11-15
Rated 5 out of 5 by from This Is Perricone Skin-care At Its Finest! Yep- can't get around the fact that it's very expensive, but used with his evening repair cream? Oh boy!! It does everything it says and more. The pronounced lines ( that only recently made their debut appearance) are visibly reduced, and is not irritating. Get it if you can swing it. QVC how about this with the Evening repair and a HYDRATING eye cream in a kit??? As a TSV? Dr. Perricone, sometimes I think your philosophy is better looking skin through dehydration....
Date published: 2014-11-12
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