Perricone MD Neuropeptide 4-piece Discovery Kit

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What is it: A complete 30-day sampler collection featuring Dr. Perricone's advanced neuropeptide technology. This collection is designed to dramatically improve the visible signs of aging and deliver the appearance of suppleness and glow of youthful-looking skin.

Who is it for: This collection is ideal for anyone looking for powerful, effective antiaging treatments that deliver both instant and long-term benefits. The collection also makes the ideal travel companion.

Why is it different: The Neuropeptide Discovery Kit features Dr. Perricone's effective antiaging treatments. It targets the look of deep lines, wrinkles, loss of firmness and suppleness, and loss of smoothness.

In an independent consumer use study, 77% of people who used Neuropeptide Deep Wrinkle Serum reported an improvement in the appearance of lines and wrinkles five minutes after application. After eight weeks of use, 90% of subjects reported that, with continued use, they continued to see improvement in the appearance of lines and wrinkles overall.

In an independent consumer use study, 82% of people using Neuropeptide Face Activator reported a slight to very noticeable change in the radiance of their skin five minutes after application. 75% noticed a slight to extremely noticeable improvement in the texture/smoothness of skin five minutes after application.

In an independent consumer use study, 97% of subjects using Neuropeptide Firming Moisturizer reported their skin appeared firmer after four weeks of use. 90% reported an improvement in the appearance of skin tone after four weeks of use.

How do I use it: Gently massage facial cleanser onto damp skin. Rinse with warm water. Use morning and evening.

Shake face activator well. Apply liberally with a cotton pad to entire face and neck area both morning and evening.

Apply deep wrinkle serum to targeted areas of the face where deep wrinkles exist.

Apply firming moisturizer liberally to the face and neck. Use morning and evening.

From Perricone MD.


  • 0.25-fl oz Neuropeptide Firming Moisturizer
  • 0.25-fl oz Neuropeptide Deep Wrinkle Serum
  • 2-fl oz Neuropeptide Facial Cleanser
  • 2-fl oz Neuropeptide Face Activator
  • Made in USA

Delivery Date Estimate

Reviews & Community QA

A218766 - Perricone MD Neuropeptide 4-piece Discovery Kit 3.3 5 18 18
Disappointed... What got me to try this line was their claim that I would likely perceive at least some difference after 5 minutes. Well, I did not hold them to that time limit. I used the products as directed, twice daily, but on only one side of my face, to compare sides. No perceptible changes after 5 minutes, 10 minutes, 1/2 hour, 1 day, 3 days, etc. Stopped after two weeks. The moisturizer left my skin soft and had a nice scent, but so does old-fashioned cold cream! These products were, for me, no more effective than that. I realize some are fans of Perricone products and so YMMV, but for me, no value here. I returned what I had left. 06-26-12
Disappointed I was very excited about getting this product, but so far disappointed for what it cost. I'm going to give it one more week. ( Have had less than a week) I'm hoping for some results! 06-09-12
Not impressed I have to say I was so excited to receive my order and have been using it twice a day. I am not impressed. Although my skin feels so soft after using it I don't see my fine lines and wrinkles changing at all. It's just not worth the money so it's going back. I really hate to have to pay for the return shipping but it's cheaper than paying the other $40+. easy pay. Don't waste your money. A drug store cleanser wiil work just as well and at a better price. 06-07-12
Classey Lady TOOOOO Pricey---DID NOT WORK!!!! I DID return it . Did not want to give it ANY stars. Save your money Ladies.! 06-06-12
Will always keep handy I have been using full size Perricone products for almost 8 weeks now, on my 65 yr. old skin. I'm on the very dry side, and had kept up my skin with visits to an esthetician...Now I have moved out of state, and just didn't want to find another skin care specialist. My mother had beautiful skin, but never went out in the sun. I , loved to water ski during school years, so have suffered sun damage. As heavy foundations went out of favor, for mineral makeup, I enjoyed those until this year. I just didn't like the look of the lines that the minerals were revealing. While hunting for liquid foundation or lighter product on QVC I came on a Perricone show. The first product I purchased was the Neuropeptide Deep Wrinkle Serum, included in this discovery kit. If I were just starting out, I dont honestly know if the small sizes would be sufficient for me to see results. However, since I had a full size, and longer time to use, the results have been outstanding...One side of the "elevens lines" is totally erased, and the other greatly receeded. I realize the odor is slightly strong on the NP Face Activator, but it goes away as it dries, and preps the skin beautifully to greater absorb the other treatment products. I use Cold Plasma, & Acyl-G both for face, & have seen my double droopy eyelids perk up with the Acyl-G eyelid serum. Don't give up. Skin care repair on this deep a level takes time, and Dr P. knows how to address these concerns. The price is worth it. I also would transfer small amounts into the smaller containers rather than exposing the products to air each time, in the full sizes. 05-27-12
Sample Sizes To me this was not a good value. The products are all the small sample sizes that are often gift with purchase. I supposed it might do if you wanted it for travel, but mine is going back 03-02-12
Great Products I am 69 years old and have used Dr Perricone's products for the past year and I can definately see a difference in my skin. When I tell people how old I am they don't believe me. I have always taken good care of my skin and with this product I will continue. 02-18-12
NOT IMPRESSED, sorry... I had HIGH EXPECTATIONS for this product, but didn't DELIVER as it said it would...COMPARATIVELY with other brands I use, considering how pricey it is... I am sending it back, sorry... 02-14-12
Perricone MD Would highly recommend!! Have used these products for about a week and can really tell a difference. I am 55 years old and need all the help I can get. It leaves my face feeling softer and does diminish the fine lines. 02-05-12
Great little kit This is a great little kit. Discovery, starter, or travel. I gave it 4 stars because I wish the moisturizer was a little larger so all the products would last the same amount of time. I am finding them enjoyable to use and no adverse reaction to any of them. 01-25-12
I finally found a product that works for me. I have 58 year old skin. For the past several years I have tried more products for my aging face than I care to admit. I ordered this product because it wasn't full size...it was the right size for me to give it a try. After two weeks of use I received a two compliments how good my skin looked. Let me just say I have NEVER received a compliment on my skin....never! After just a couple days use I noticed a significant difference in my complexion. My face feels so soft. I feel very strongly about this product and have ordered the 'full size' products. 12-31-11
GRASP AN ENCHANTMENT WITH PERRICONE KITS… …AND THE PRODUCTS IN THIS FORWARD-POTENT-NEUROPEPTIDE FOURSOME… is a combo that works effectively together, and/or alone. I’ve used each one of the Perricone MD products in this kit, and have graduated from the kit size to larger, individual sizes. I recommend this foursome and the kit for any skin type, and encourage you to make a kit investment at a substantial good value. I am addicted to Perricone healthy-skin formulas; there is not one that has not made a tremendous difference on/in my seventy-year young skin. That addiction is the result of the visible differences and improvements each has made to achieve my healthy derma visible results. The kit takes you thirty days (or more dependent on regimen habits) with dual use a.m. and p.m. I recently purchased one of these kits for my friend in North Carolina and sent it direct mail. She now uses Perricone MD technology, as I do. I keep kits available to me in case of a quick-call travel plan. (I also use some of philosophy™ products in combo with Perricone or alone.) Each item in this NEUROPEPTIDE quad complement each other, and yes, you can use with other products effectively. The CLEANSER is a to-die-for formula, leaving (and a scent like) skin baby powder soft. The DEEP WRINKLE SERUM acts quickly and continues to nurture my deep wrinkles to a minimum depth and length. The FACE ACTIVATOR I apply with a cotton ball/pad (and you shake the bottle, yes it is a fun exercise for the hand and fingers :-) is soothing, refreshing, and face/neck skin-prepping for application of other treatments. Then the FIRMING MOISTURIZER… wow, it is among or over the top of the line for skin tone and definitively firming for the face and neck! My estimation time for improvement in my skin for each Perricone MD varies from one to four weeks, and I keep on trekking with my maintenance regimen. The dollar investment is more than returned just by looking at my face, neck, and décolleté for improvement in: suppleness, texture, firmness, smoothness, overall wrinkles, radiance, and I judiciously intend to faithfully keep up the routine for long-term benefits. (And the QVC-available Perricone CHIA serum is grand!) 12-08-11