Dr. Denese Wrinkle Rx Extreme Pro-Peptide Gel 1.7 oz

Because QVC's special offers are only available for a limited time, previously recorded videos may contain pricing, exclusivity claims or promotional offers that have expired.
product thumbnail

Delivery Options:
What is it: A unique and concentrated seven-peptide technology suspended in a face gel to help combat signs of aging that are visible on your face, like expression lines and deep defined lines and wrinkles. The gel contains our unique Stem Bio-Technology which works with our Pro Peptide Factor to help refine the skin and improve the overall quality of the skin.

Who is it for: Anyone who has deep, visible, defined lines and wrinkles and wants to dramatically change the look of the quality of their skin.

Why is it different: A highly advanced peptide system targets expression lines, which need to be treated differently than fine lines and wrinkles. Our Pro-Peptide Factor combined with Stem Bio Technology targets, softens, and makes a visible change on the appearance of deep, defined expression lines on the face. The unique gel delivery system allows the product to penetrate into the skin effectively.

How do I use it: Apply day and night after Advanced Firming Facial pads. Follow with serums and any night and day creams.

From Dr. Denese.

  • Net weight 1.7 fl oz pro-peptide gel

Delivery Date Estimate

Reviews & Community QA

Rated 3.6 out of 5 by 245 reviewers.
Rated 5 out of 5 by GREAT GREAT GREAT ! I came to use this because I couldn't tolerate the ingredients in Dr Perricone Formulas. I am thrilled because this is effective without weird sensations and scents. The slight scent is not bothersome and goes away as soon as the product dries and that is really quick. I like the color because it tells you where you put it on then disappears. I looked great the next day and I can feel the firmness. Then you add the moisturizer on top and it really feels firming. I want to use her whole skin care line now. 07-27-16
Rated 5 out of 5 by Wrinkles Be Gone! I use this every morning and have seen a difference in my expression lines, forehead and above my upper lip. It is an orange color but does not look orange on your skin. It absorbs quickly without any tackiness. A little goes a long way. 03-18-16
Rated 1 out of 5 by Went Back Same Day Received I use Dr Denese products and I couldn't wait to get this one. I was so disappointed when I washed my face and used this. First off it has a horrible smell and then it made my face sticky like I had rubbed honey all over it instead. Even my husband noticed this. So glad QVC has such a great return policy! 11-30-15
Rated 5 out of 5 by Wrinkles dramatically reduced and my skin glows!!! This Pro-Peptide Gel is FABULOUS. My lines have diminished dramatically. 11 is now a one and the ONE line is so much more diminshed. It is a very powerful product without any sensitivity to my skin. My skin glows and is so much more brighter. Nasolabial folds decreased dramatically. Firmness is evident. Peptides are needed for anti-aging especially anti-wrinkle which work by stimulating collagen production and boosting skin's elasticity. The plants products are important for DNA repair which reverse damage because evidence shows that plants correct new and old damage by working on human cells for reversal of aging or DNA repair. As far as complaints on too sticky or bad odor... I DO NOT have any problems with stickiness. I use small amount on my expression lines, I let it soak in for a minute or two then, I smooth the product all over my entire face and the brightness is evident. As far as a bad smell complaint... Initially, the first two times using the product, I thought the scent was a different, strong aroma. I was hesitant but put a small dap of a different cream under my nose and the aroma was gone. By the second day of using the product I did not notice the aroma. I think the aroma is a Licorice scent. Licorice brightens the skin and evens out skin tone. I am consistent with product application and with consistent use Dr. Denese's products work. I LOVE DR. DENESE'S PRODUCTS!!! 06-04-15
Rated 5 out of 5 by Wrinkle RX pro peptide gel I bought this product after I left a message on Dr Denese Fb page asking what do I use for deep wrinkles. And she. Suggested this product. Well it works wonders for me. 04-07-15
Rated 5 out of 5 by Recommend I am 41 years old and have been actively trying to pause the clock. I have fallen in love with Dr. Denese products. They truly provide results. This product is like no other product that I have used and yes, has a different smell and texture to it but lessens the wrinkles on my forehead. I recommend it! 02-14-15
Rated 5 out of 5 by STICKY? YOU ARE USING TOO MUCH. I received free samples of this product and found that I really liked it. Those little lines at the corner of my lips softened so much and I just liked the feel of my skin when using this followed by Hydroshield. Yes, it does have an odor, but that is usually gone by the time I leave for work. And as another viewer stated, it smells like licorice. It can be sticky - but only if you use to much product or don't let it dry before you use another product. I am using pretty much everywhere including the area under my eyebrows and I do believe I see a differernce. I am using this in the AM followed by Hydroshield. In the PM I use the Firmatone RX. I will be 62 in a couple months and folks are always telling me that I don't look near that. In fact, several times when my duaghter has been hospitalized, doctors come in and think I am her sister. My duaghter is 37! 08-13-14
Rated 5 out of 5 by Instant Glow Yes the gel is thick, but you only need a drop and it instantly brightens your face. It can be used morning or night. People who don't like the smell are nuts, the smell is licorice and licorice is an ingredient in many spot reducing products. Wouldn't you rather have the smell of a real, effective ingredient instead of perfume! I have used many of Dr Denese's products and they all work! 01-25-14
  • 2017-01-22 T14:23:01.725-06:00
  • bvseo_lps, prod_bvrr, vn_prr_5.6
  • cp-1, bvpage1
  • co_hasreviews, tv_245, tr_245
  • loc_en_US, sid_A89458, prod, sort_default
MORE REVIEWS>> 2 3 4 5 ... 31

Let's Stay in Touch

* *You're signing up to receive QVC promotional email.
Connect with Us

The scoop on everything Q, from helpful tips to interesting tidbits, questions, answers, and more.

QVC is not responsible for the availability, content, security, policies, or practices of the above referenced third-party linked sites, nor liable for statements, claims, opinions, or representations contained therein. QVC's Privacy Statement does not apply to these third-party web sites.

© 1995–2017 QVC, Inc. All rights reserved. Trademark Notice

Desktop View Mobile View